18.3% of ADULTS IN MALAYSIA ARE DIABETES
2.3 mil MALAYSIAN ARE HAVING DIABETES, HIGH BLOOD PRESSURE AND HIGH CHOLESTEROLS
UNDERSTANDING DIABETIC
How insulin works
Main Ingredients
Pterocarpus Marsupium
(Vijaysar)
Vijaysar is useful in the treatment
of Prameh, all types of Kustha,
Guda Vikar, Rakta, and Pitta Vikar.
Because of its antioxidant and
anti-inflammatory properties, Vijaysar
aids in:-
- blood sugar management by
preventing pancreatic cell damage and promoting insulin secretion.
- regenerate beta cells in pancreas.
- reduce cholesterols and fat levels in
the body.
Gymnema Sylvestre
(Gurmar)
Gymnema leaves contain several
bioactive compounds, including gymnemic acids, that may offer several healthbenefits.
- help regulate blood sugar levels by improving insulin sensitivity.
- increase glucose uptake in the cells.
- appetite control.
- cholesterol reduction.
- anti-inflammatory effects and digestive health.
Momordica Charantia
(Karela / Bitter Melon)
Bitter Gourd contains several bioactive compounds, including charantin and momordicin,
that may offer several potential health benefits.
- help regulate blood sugar levels by
improving insulin sensitivity.
- increasing glucose uptake in the cells.
- cholesterols reduction.
- anti-inflammatory effects.
- improve immune system support.
- promote skin health.
Terminalia Arjuna
(Arjuna)
Arjuna contains several bioactive compounds, including flavonoids and tannins, which
may offer several potential health
benefits.
Terminalia Arjuna extract has been shown to have:
- cardioprotective effects.
- may help improve heart function.
- help reduce blood pressure.
- improve blood circulation.
- lower cholesterol level.
- anti-inflammatory effects.
- helps on liver health.
- potential anti-cancer effects.
- anti-aging effects.
PRODUCT CERTIFICATION
Halal Certification
GMP Certification
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HACCP Certification
ISO22000 Certification
CLINICAL TEST ON PTEROCARPUS MARSUPIUM (VIJAYSAR) AND GYMNEMA SYLVESTRE (GURMAR)
RESEARCH CENTRE: CENTRE OF TRANSLATIONAL RESEARCH, JIWAJI UNIVERSITY INDIA
SUBMISSION DATE: SEPTEMBER 26, 2017
PUBLISHED DATE: AUGUST 28, 2018
RESEARCH NO: JCMAH 2018.07.555718
MIXTURE TEST: PTEROCARPUS MARSUPIUM (VIJAYSAR) AND GYMNEMA SYLVESTRE (GURMAR) - "VG"
A total of 45 type 2 diabetic patients the weekend diabetes clinic run by the Centre for Translational Research, School of Studies in Biochemistry, Jiwaji University, India expressed their willingness to participate in the study. Of these, 35 subjects met the inclusion criteria who were then explained the necessity of maintaining defined lifestyle pattern during the course of the study. Out of 35 subjects, 8 subjects were eliminated during the course of the study due to non-compliance. The remaining 27 subjects took the herb regimen regularly as per the experimental design.
Effect of VG therapy on hyper-glycemia
Table 3 shows the fasting and postprandial blood glucose levels at monthly intervals in subjects on “VG” therapy. A significant decrease was recorded for fasting (13.5% P<0.05), postprandial (15.0%, <0.001) glucose levels and glycosylated hemoglobin (9.8%) at the end of six months therapy
Effect of VG therapy on lipidemia
Table 4 shows the results of the lipid profile of patients on “VG” therapy. Total cholesterol, triglycerides, LDL and VLDL were significantly decreased after six months therapy by 9.6%, 14.4%, 15.7%, and 14.4% respectively (P<0.05). HDL cholesterol was elevated from32.50±1.11 to 35.69 ± 1.02 (P<0.001).
Effect of VG therapy on biomarkers of oxidative stress
Significant (P<0.05, P<0.001), improvements in GSH level (from 1.98±0.17 to 2.59±0.21 mg/dl), SOD activity (from 0.63±0.05 to 0.94±0.08 µM/min/mg protein), catalase activity (from 7.64±0.24 to 9.44±0.23 µM/min/mg protein) were recorded. A significant decrease (P<0.001) in TBARS (from 457.19±8.09 to 415.15±7.47 (moles of Malondialdehyde/ml of blood) were recorded at the end of six months therapy.
Effect of VG therapy on markers of toxicity
The effect of “VG” therapy on kidney function was monitored by estimating urea, uric acid and creatinine levels in plasma at specified intervals during the course of therapy. The data presented in Table 5 showed significant (P<0.05), reductions in Urea (from 29.97±1.20 to 27.10±0.88mg/dl) and uric acid (from 5.08±0.20 to 4.67±0.20 mg/dl) and notable reduction in creatinine (from 0.78±0.06 to 0.73±0.05) at the end of six months therapy. Significant (P< 0.05), variations in biochemical markers of liver functions, namely bilirubin (from 0.83±0.06 to 0.70±0.04 mg/ml) and SGOT (from 22.47±1.61 to 18.00±1.04 IU/L) as well as SGPT (from 23.60±2.32 to 19.26±1.38 IU/L), at the end of six months was observed (Table 6).
Effect of VG therapy on hypertension and body mass index
Table 7 shows variations in systolic blood pressure (from 133.70±2.59 to 129.22±2.39 mmHg), diastolic blood pressure (from 81.70±0.97 to 79.56±0.93 mmHg) and body mass index (from 25.21±0.64 to 24.22±0.60 kg/m2) at the end of the six months therapy
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Conclusion
In conclusion, the “VG” administration to type 2 diabetic patients with varying degrees of glycemia, lipidemia and oxidative stress provide an efficient alternative to conventional antidiabetic drugs when coupled with active lifestyle and dietary changes. Significant decrease in biochemical markers viz., blood glucose, HbA1c, total cholesterol, triglycerides, LDL-cholesterol, and VLDL-cholesterol and higher values of HDL, following VG therapy are testimony to the anti-diabetic efficacy of VG. Further, the formulation did not show any adverse effects on liver and kidney functions and may be a potential natural and safe therapy for treatment and prevention of diabetic complications but randomized controlled trials are required to confirm these findings.
ORDER FOR GREATER HEALTH
Benefits
- Regenerate Beta Cells in pancreas to produce insulin
- Lower Blood Sugar Levels
- Lower Bad Cholesterols
- Lower Triglycerides
- Lower and Stabilize Blood Pressure
- Improve Blood Circulations
- Anti-Inflammation
- General Overall Health
Main Ingredients
- Pterocarpus Marsupium
- Gymnema Sylvestre
- Momordica Charantia
- Terminalia Arjuna